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The stem cellstem cell
Cells which can divide repeatedly without becoming differentiated and have the capacity to develop into a diverse range of specialised cell types.
s of an early embryoembryo
The name for a group of cells that are developing into a fetus. In humans this is from implantation to the 8th week of development.
are all very similar and all have the potential to become any other cell in the body – they are pluripotentpluripotent
(of an immature cell or stem cell) capable of differentiating to form almost any type of cell in the body except those of the placenta and amniotic membranes.
. But by the time a baby is born, many of the cells have differentiated and become specialised for particular functions in the body. Examples include muscle cells that contract in response to a stimulus, neurones that carry electrical impulses around the body, and secretory cells that produce substances such as mucus, acid, enzymes or hormones for the body to use.
Different cells are adapted for different functions in an organism, such as the sensory cells (green) highlighted in this confocal micrograph of a Drosophila melanogaster fruit fly (Chun Han, CC BY-NC-ND 3.0)
It is very useful to consider some of the major adaptations for different functions seen in cells. Looking at differences in the ultrastructureultrastructure
The structure of a cell as seen using an electron microscope.
of a cell can give you a clear insight into the functions of that cell in the body.
Example 1: Transport
There are many situations where it is important to move substances into or out of cells. For example the products of digestion moving into the cells of the ileum, the hormones produced by glandular cells moving into the bloodstream or the Na+, K+ or Cl- ions involved in the electrochemical events of an action potentialaction potential
The wave of positive charge which passes along an axon in response to a stimulus.
moving into or out of a neurone.
Cells may be adapted to allow rapid transport across their internal or external membranemembrane
A thin, flexible sheet-like structure that acts as a lining or a boundary in an organism.
s in a number of ways:
Example 2: Energy requirements
Some cells require relatively little ATP to carry out their functions. Others need a lot of ATP for anabolic reactionsanabolic reactions
Reactions where two smaller molecules are joined together to form a larger molecule (
or for functions such as the contraction of the muscles. As a general rule, cells that require a lot of ATP such as heart muscle and secretory cells contain many mitochondriamitochondria
Organelle(s) within cells that produce ATP, used as a store of chemical energy. Often called the cell's powerhouse
, whilst cells that have low activity levels have few mitochondria.
Many fat cells have few mitochondriamitochondria
Organelle(s) within cells that produce ATP, used as a store of chemical energy. Often called the cell's powerhouse
, but special brown fat cells found in newborn babies and hibernating animals are full of mitochondria which undergo a special form of aerobic respiration designed to produce heat to keep the body warm (Image credits: mitochondria Keith Porter/ CC BY-NC-ND 3.0 hedgehog Jamain/ CC-BY-SA-3.0,2.5,2.0,1.0)
Example 3: Secretory functions
Cells that produce large amounts of proteins or other compounds such as steroid hormones, neurotransmittersneurotransmitters
Chemicals which are released in a synapse when an action potential reaches the end of one neurone. They cross the synaptic gap and trigger and impulse in the next neurone.
, acid or mucus, usually have high levels of rough endoplasmic reticulumrough endoplasmic reticulum
A network of membranes within a cell which has ribosomes attached to it. They are important in the synthesis and transportation of proteins.
and Golgi apparatus in their cytoplasm. They may also have large numbers of vesicles containing secretions. These features are much less common in other types of cells.